Here are some design guidelines and practises which the Microfluidics Consortium recommends
Getting Started with Microfluidics — James Gwyer et Al, MF3 Microfluidics Consortium
*. Design Guidelines – Parallel Fluidics
* Design for Manufacture of Microfluidic Devices—MF5 White Paper
* Guidelines for Design in Glass (Submitted by Dolomite Microfluidics)
* Guidelines for Design in Polymer (Submitted by SonyDADC)
* Micro and Nano Manufacturing Guidelines (Submitted by EVGroup)
Design Automation for a Microfluidics Droplet Generator – DAFD Tutorial
Open Source Designs for Microfluidic Systems – from MIT
Introducing Spresso — Open Source Simulation Software for
Electrophoretic Separation. Stanford University